Publications PreClinical

Abstracts

Wolfson; Perfluorochemical (PFC) Nasopharyngeal (NP) Cooling Induces Selective Brain Hypothermia, Pediatric Academic Societies’ Meeting, Poster, May 2006

Wolfson; A Novel Approach for Inducing Selective Brain Hypothermia, Hot Topics in Neonatology, Poster, Dec 2006

Tsai; Rapid Intranasal Cooling Initiated Coincident with CPR Improves Success of Defibrillation and Post-resuscitation Myocardial Function In A Porcine Model of Prolonged Cardiac Arrest , American Heart Association (AHA) (Scientific Sessions (SS)), Poster, Nov 2007

Guan; Rapid Induction Of Head Cooling By The Intranasal Route During Cardiopulmonary Resuscitation Improves Survival and Neurological Outcomes , AHA SS, Oral abstract, Nov 2007

Boller; Feasibility of Selective Brain Cooling during Cardiac Arrest: A Novel Nasopharyngeal Approach, AHA (ReSS), Poster, Nov 2007

Tsai; Rapid Brain Cooling during Cardiopulmonary Resuscitationfollowed by Systemic Therapeutic Hypothermia Reduces Myocardial Damage in a Porcine Model of Prolonged Ventricular Fibrillation, Society of Critical Care Medicine (SCCM) Congress, Poster, Feb 2008

Tsai; Intra-arrest Rapid Head Cooling Improves Amplitude Spectrum Area of Ventricular Fibrillation and Facilitates Defibrillation, SCCM, Poster, Feb 2008

Tsai; Intra-arrest Rapid Head Cooling Improves Cardiac Arrest Outcomes over Delayed Post-Resuscitation Systemic Cooling in a Porcine Model of Prolonged Ventricular Fibrillation, SCCM, Poster, Feb 2008

Wang; Intra-arrest Intra-nasal Cooling Improves Resuscitation afterProlonged Cardiac Arrest in Pigs, SCCM, Poster, Feb 2008

Guan; A Comparison between Head Cooling begun during CPR andSurface Cooling after Resuscitation, SCCM, Poster, Feb 2008

Guan; Intranasal Spray of Perfluorocarbon can Rapidly Reduce BrainTemperature and Culminate in SystemicHypothermia in a Pig Model of Prolonged Cardiac Arrest, SCCM, Poster, Feb 2008

Wang; Intra-Arrest Intranasal Cooling Improves Success of Resuscitation in a Porcine Model of Prolonged Cardiac Arrest, European Resuscitation Council (ERC) Congress, Oral abstract, May 2008

Yu; Exploratory study on mechanism by which hypothermia improves outcomes of cardiopulmonary resuscitation, AHA (ReSS), Poster, Nov 2008

Cho; Early selective head cooling during CPR improves success of resuscitation in a porcine model of pulseless electrical activity cardiac arrest , AHA (SS), Oral abstract, Nov 2008

Tantillo; Early selective head cooling during CPR improves post-ROSC hemodynamic stability and decreases recurrence of ventricular fibrillation, AHA (SS), Oral abstract, Nov 2008

Ristagno; Selective head cooling initiated during CPR induces postresuscitation carotid artery dilation and increases in carotid artery flow and cerebral cortical microcirculation, AHA (ReSS), Poster, Nov 2008

Ristagno; Safety and efficacy of head cooling in a porcine model of cardiopulmonary resuscitation with chest compression only and without airway protection, AHA (ReSS), Poster, Nov 2008

Yu; Comparison between trans-nasal cooling and IV infusion of cold saline initiated during CPR on resuscitation outcomes in a porcine model of prolonged cardiac arrest , SCCM, Poster, Feb 2009

Cho; Survival and neurological outcomes after trans-nasal cooling initiated during CPR and maintained for either one or four hour following resuscitation ,SCCM, Poster, Feb 2009

Cho; Early intra-nasal cooling during CPR using either oxygen or air as a propellant of the evaporative cooler, SCCM, Poster, Feb 2009

Yu; Nasopharyngeal cooling improves coronary perfusion pressure and amplitude spectrum area during CPR in comparison to systemic cold saline Infusion in a porcine model of prolonged cardiac arrest , AHA (ReSS), Poster, Nov 2009

Manuscripts

Wolfson; Intranasal Perfluorochemical Spray for Preferential Brain Cooling in Sheep, Neurocrit Care, Humana Press Inc. 2008

Tsai; The amplitude spectrum area correctly predicts improved resuscitation and facilitated defibrillation with head cooling, Crit Care Med 2008; 36: [Suppl.]:S413–S417 Nov 2008

Wang; Intra-arrest selective brain cooling improves success of resuscitation in a porcine model of prolonged cardiac arrest, Resuscitation 2010;81: 617-21 May 2010

Tsai; Rapid head cooling initiated coincident with cardiopulmonary resuscitation improves success of defibrillation and postresuscitation myocardial function in a porcine model of prolonged cardiac arrest, JACC 2008;51(20):1988-90 May 2008

Tsai; Intra-arrest rapid head cooling improves post resuscitation myocardial function in comparison with delayed post resuscitation surface cooling, Crit Care Med 2008; 36[Suppl.]:S434 –S439) Nov 2008

Guan; Rapid induction of head cooling by the intranasal route during cardiopulmonary resuscitation improves survival and neurological outcomes. , Crit Care Med 2008; 36:[Suppl.]:S428 –S433) Nov 2008

Yu; Survival and neurological outcomes after nasopharyngeal cooling or peripheral vein cold saline infusion initiated during CPR in a porcine model of prolonged cardiac arrest. , Crit Care Med 2010; 38: 916-21 Mar 2010

What the scientific community is saying about RhinoChill (editorial)

Boller; Feasibility of intra-arrest hypothermia induction: A novel nasopharyngeal approach achieves preferential brain cooling., Resuscitation 2010;81: 1025-30 Aug 2010